Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome that is caused by the presence of a tumor that secretes a hormone that leads to the development of osteomalacia, a condition characterized by weakened bones and an increased risk of fractures. The tumor secretes fibroblast growth factor 23 (FGF23), which causes the kidneys to excrete phosphate, leading to hypophosphatemia and impaired bone mineralization.
Worldwide revenue from the tumor-induced osteomalacia market reached US$ 111,372.2 thousand in 2021, with the global market estimated to move ahead at a value CAGR of 2.8% to reach US$ 176,483.9 thousand by the end of 2032.
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The TIO market is segmented based on the type of treatment used, such as surgical treatment and medical treatment. The surgical treatment segment dominates the market due to its effectiveness in treating the underlying cause of the disease, which is the removal of the tumor. However, medical treatments such as phosphate and vitamin D supplements may be necessary to manage symptoms even after surgery.
The market is also segmented based on the type of tumor that causes TIO, with the most common tumors being mesenchymal tumors and hemangiopericytomas. The mesenchymal tumor segment dominates the market due to the high incidence of TIO caused by these tumors. However, hemangiopericytomas are also becoming more commonly recognized as a cause of TIO.
Companies
- Ultragenyx Pharmaceutical Inc.
- Dishman Carbogen Amcis Ltd.
- Teva Pharmaceuticals
- Glenmark Pharmaceuticals
- Wockhardt Ltd
- FDC Limited
- Lupin Pharmaceuticals
- Zydus Cadila Healthcare Ltd.
- Intas Pharmaceuticals Ltd
- Macleods Pharmaceuticals
- C. Chemie Pharmie Ltd
- Santiago Life Sciences
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The TIO market is small but growing, with an increasing number of cases being diagnosed every year. The market is driven by factors such as the increasing awareness of the disease and the availability of advanced diagnostic techniques. However, the high cost of treatment and the rarity of the disease are major challenges to the growth of the market.
The major players in the TIO market are focused on developing new treatments and therapies to better manage the disease and improve patient outcomes. They are also focused on increasing awareness of the disease among healthcare professionals and the general public to improve early diagnosis and treatment.
In conclusion, the TIO market is small but growing, with an increasing number of cases being diagnosed every year. The primary treatment for TIO is the surgical removal of the tumor, but there are also medical treatments available to manage symptoms. The market is driven by factors such as the increasing awareness of the disease and the availability of advanced diagnostic techniques, but the high cost of treatment and the rarity of the disease are major challenges to the growth of the market. The major players in the market are focused on developing new treatments and therapies to better manage the disease and improve patient outcomes.
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Tumor-induced Osteomalacia Industry Research Segmentation
Tumor-induced Osteomalacia Market by Treatment:
- Drugs and Supplements
- Burosumab -za
- Cinarcalcet
- Calcium
- Active Vitamin D (Calcitriol/α-calcitriol)
- Phosphorus
- Surgery
Tumor-induced Osteomalacia Market by Diagnosis:
- Laboratories
- Elevated Blood Fibroblast Growth Factor 23 (FGF-23)
- Serum Calcium, PTH, Vitamin D
- Hyperphosphaturia (Secondary Effects of FDF-23)
- Hypophosphatemia (Secondary Effects of FDF-23)
- Bone Scan
- Magnetic Resonance Imaging (MRI)
- Computed Tomography (CT Scans)
- Differential Diagnosis
- Vitamin D Metabolism and Deficiency
- Osteoporosis
- Renal Osteodystrophy
- Others
Tumor-induced Osteomalacia Market by End User:
- Hospitals
- Specialty Clinics
- Others
Tumor-induced Osteomalacia Market by Country:
- U.S.
- Canada
- Japan
- European Countries
- China
- Mexico
- South Korea
- India
- Brazil
- Australia
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